Publications de l'UMR 1118
66 publications disponibles
Articles scientifiques
- Editorial: RNA metabolism and DNA stability in the central nervous system (CNS): from aging to neurodegenerative disease, Frontiers in Molecular Biosciences | 2024
Auteur(s) : Tangliang Li - Wenting Guo - Haibo Wang - FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease, Nature Communications | 2024
Auteur(s) : Manohar Kodavati - Haibo Wang - Wenting Guo - Joy Mitra - Pavana M. Hegde - Vincent Provasek - Vikas H. Maloji Rao - Indira Vedula - Aijun Zhang - Sankar Mitra - Alan E. Tomkinson - Dale J. Hamilton - Ludo Van Den Bosch - Muralidhar L. Hegde - lncRNA Sequencing Reveals Neurodegeneration-Associated FUS Mutations Alter Transcriptional Landscape of iPS Cells That Persists in Motor Neurons, Cells | 2023
Auteur(s) : Vincent E. Provasek - Manohar Kodavati - Wenting Guo - Haibo Wang - Istvan Boldogh - Ludo Van Den Bosch - Gavin Britz - Muralidhar L. Hegde - Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression., Neurobiology of disease | 2021
Auteur(s) : Júlia Canet-Pons - Nesli-Ece Sen - Aleksandar Arsović - Luis-Enrique Almaguer-Mederos - Melanie V Halbach - Jana Key - Claudia Döring - Anja Kerksiek - Gina Picchiarelli - Raphaëlle Cassel - Frédérique René - Stephane Dieterle - Nina V Fuchs - Renate König - Luc Dupuis - Dieter Lütjohann - Suzana Gispert - Georg Auburger - Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects., Nature communications | 2021
Auteur(s) : Jelena Scekic-Zahirovic - Inmaculada Sanjuan Ruiz - Vanessa Kan - Salim Megat - Pierre De Rossi - Stéphane Dieterlé - Raphaëlle Cassel - Marguerite Jamet - Pascal Kessler - Diana Wiesner - Laura Tzeplaeff - Valérie Demais - Sonu Sahadevan - Katharina M Hembach - Hans-Peter Muller - Gina Picchiarelli - Nibha Mishra - Sylvie Dirrig-Grosch - Jan Kassubek - Volker Rasche - Albert Ludolph - Anne-Laurence Boutillier - Francesco Roselli - Magdalini Polymenidou - Clotilde Lagier-Tourenne - Sabine Liebscher - Luc Dupuis - R01 NS108769 - Disruption of orbitofrontal-hypothalamic projections in a murine ALS model and in human patients., Translational neurodegeneration | 2021
Auteur(s) : David Bayer - Stefano Antonucci - Hans-Peter Müller - Rami Saad - Luc Dupuis - Volker Rasche - Tobias M Böckers - Albert C Ludolph - Jan Kassubek - Francesco Roselli - 251293561 - 431995586 - GRK 1789/2 - 443642953 - 01EW1705A - TriALS - Hypothals - Dysregulation of energy homeostasis in amyotrophic lateral sclerosis., Current opinion in neurology | 2021
Auteur(s) : Simon Guillot - Matei Bolborea - Luc Dupuis - Evidence that corticofugal propagation of ALS pathology is not mediated by prion-like mechanism, Progress in Neurobiology | 2021
Auteur(s) : Jelena Scekic-Zahirovic - Mathieu Fischer - Geoffrey Stuart-Lopez - Thibaut Burg - Johan Gilet - Sylvie Dirrig-Grosch - Christine Marques - Marie-Christine Birling - Pascal Kessler - Caroline Rouaux - Hypothalamus and weight loss in amyotrophic lateral sclerosis., Handbook of clinical neurology | 2021
Auteur(s) : Rebekah M Ahmed - Frederik Steyn - Luc Dupuis - Linking neuroinflammation to motor neuron degeneration in ALS: The critical role of CXCL13/CXCR5., EBioMedicine | 2021
Auteur(s) : Alizée Arnoux - Luc Dupuis - Skeletal Muscle Metabolism: Origin or Prognostic Factor for Amyotrophic Lateral Sclerosis (ALS) Development?, Cells | 2021
Auteur(s) : Cyril Quessada - Alexandra Bouscary - Frédérique René - Cristiana Valle - Alberto Ferri - Shyuan T Ngo - Jean-Philippe Loeffler - Sphingolipids metabolism alteration in the central nervous system: Amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases., Seminars in cell & developmental biology | 2021
Auteur(s) : Alexandra Bouscary - Cyril Quessada - Frédérique René - Michael Spedding - Bradley J Turner - Alexandre Henriques - Shyuan T Ngo - Jean-Philippe Loeffler - Synaptic FUS accumulation triggers early misregulation of synaptic RNAs in a mouse model of ALS., Nature communications | 2021
Auteur(s) : Sonu Sahadevan - Katharina M Hembach - Elena Tantardini - Manuela Pérez-Berlanga - Marian Hruska-Plochan - Salim Megat - Julien Weber - Petra Schwarz - Luc Dupuis - Mark D Robinson - Pierre De Rossi - Magdalini Polymenidou - Upper and Lower Motor Neuron Degenerations Are Somatotopically Related and Temporally Ordered in the Sod1 Mouse Model of Amyotrophic Lateral Sclerosis., Brain sciences | 2021
Auteur(s) : Christine Marques - Thibaut Burg - Jelena Scekic-Zahirovic - Mathieu Fischer - Caroline Rouaux - 639737 - 618764 - 16923 - 21993 - NA - Absence of Subcerebral Projection Neurons Is Beneficial in a Mouse Model of Amyotrophic Lateral Sclerosis., Annals of neurology | 2020
Auteur(s) : Thibaut Burg - Charlotte Bichara - Jelena Scekic - Mathieu Fischer - Geoffrey Stuart-Lopez - Aurore Brunet - François Lefebvre - Matilde Cordero Erausquin - Caroline Rouaux - Altered skeletal muscle glucose-fatty acid flux in amyotrophic lateral sclerosis., Brain communications | 2020
Auteur(s) : Frederik J Steyn - Rui Li - Siobhan E Kirk - Tesfaye W Tefera - Teresa Y Xie - Timothy J Tracey - Dean Kelk - Elyse Wimberger - Fleur C Garton - Llion Roberts - Sarah E Chapman - Jeff S Coombes - W Matthew Leevy - Alberto Ferri - Cristiana Valle - Frédérique René - Jean-Philippe Loeffler - Pamela A McCombe - Robert D Henderson - Shyuan T Ngo - Association of Insulin-like Growth Factor 1 Concentrations with Risk for and Prognosis of Amyotrophic Lateral Sclerosis - Results from the ALS Registry Swabia., Scientific reports | 2020
Auteur(s) : Gabriele Nagel - Raphael S Peter - Angela Rosenbohm - Wolfgang Koenig - Luc Dupuis - Dietrich Rothenbacher - Albert C Ludolph - Cortical Circuit Dysfunction as a Potential Driver of Amyotrophic Lateral Sclerosis., Frontiers in neuroscience | 2020
Auteur(s) : Aurore Brunet - Geoffrey Stuart-Lopez - Thibaut Burg - Jelena Scekic-Zahirovic - Caroline Rouaux - De Novo Frameshift Variants in the Neuronal Splicing Factor NOVA2 Result in a Common C-Terminal Extension and Cause a Severe Form of Neurodevelopmental Disorder., American journal of human genetics | 2020
Auteur(s) : Francesca Mattioli - Gaëlle Hayot - Nathalie Drouot - Bertrand Isidor - Jérémie Courraud - Maria-Victoria Hinckelmann Rivas - Frederic Tran Mau-Them - Chantal Sellier - Alica Goldman - Aida Telegrafi - Alicia Boughton - Candace Gamble - Sebastien Moutton - Angelique Quartier - Nolwenn Jean - Paul Van Ness - Sarah Grotto - Sophie Nambot - Ganka Douglas - Yue Cindy Si - Jameleddine Chelly - Zohra Shad - Elisabeth Kaplan - Richard Dineen - Christelle Golzio - Nicolas Charlet-Berguerand - Jean-Louis Mandel - Amélie Piton - Drug repositioning in neurodegeneration: An overview of the use of ambroxol in neurodegenerative diseases., European journal of pharmacology | 2020
Auteur(s) : Alexandra Bouscary - Cyril Quessada - Frédérique René - Michael Spedding - Alexandre Henriques - Shyuan Ngo - Jean-Philippe Loeffler - Effect of High-Caloric Nutrition on Survival in Amyotrophic Lateral Sclerosis., Annals of neurology | 2020
Auteur(s) : Albert C Ludolph - Johannes Dorst - Jens Dreyhaupt - Jochen H Weishaupt - Jan Kassubek - Ulrike Weiland - Thomas Meyer - Susanne Petri - Andreas Hermann - Alexander Emmer - Julian Grosskreutz - Torsten Grehl - Daniel Zeller - Matthias Boentert - Bertold Schrank - Johannes Prudlo - Andrea S Winkler - Stanislav Gorbulev - Francesco Roselli - Joachim Schuster - Luc Dupuis - LIPCAL-ALS Study Group - LU 336/16-1 - n/a - Effect of high-caloric nutrition on serum neurofilament light chain levels in amyotrophic lateral sclerosis., Journal of neurology, neurosurgery, and psychiatry | 2020
Auteur(s) : Johannes Dorst - Joachim Schuster - Jens Dreyhaupt - Simon Witzel - Jochen H Weishaupt - Jan Kassubek - Ulrike Weiland - Susanne Petri - Thomas Meyer - Torsten Grehl - Andreas Hermann - Berit Jordan - Julian Grosskreutz - Daniel Zeller - Matthias Boentert - Bertold Schrank - Johannes Prudlo - Andrea S Winkler - Stanislav Gorbulev - Franceso Roselli - Luc Dupuis - Markus Otto - Albert C Ludolph - Longitudinal transcriptomic analysis of altered pathways in a CHMP2Bintron5-based model of ALS-FTD., Neurobiology of disease | 2020
Auteur(s) : Robin Waegaert - Sylvie Dirrig-Grosch - Florian Parisot - Céline Keime - Alexandre Henriques - Jean-Philippe Loeffler - Frédérique René - Multiplexed chemogenetics in astrocytes and motoneurons restore blood-spinal cord barrier in ALS., Life science alliance | 2020
Auteur(s) : Najwa Ouali Alami - Linyun Tang - Diana Wiesner - Barbara Commisso - David Bayer - Jochen Weishaupt - Luc Dupuis - Phillip Wong - Bernd Baumann - Thomas Wirth - Tobias M Boeckers - Deniz Yilmazer-Hanke - Albert Ludolph - Francesco Roselli - Role of RNA Binding Proteins with prion-like domains in muscle and neuromuscular diseases., Cell stress | 2020
Auteur(s) : Gina Picchiarelli - Luc Dupuis - Skeletal-Muscle Metabolic Reprogramming in ALS-SOD1G93A Mice Predates Disease Onset and Is A Promising Therapeutic Target., iScience | 2020
Auteur(s) : Silvia Scaricamazza - Illari Salvatori - Giacomo Giacovazzo - Jean-Philippe Loeffler - Frédérique René - Marco Rosina - Cyril Quessada - Daisy Proietti - Constantin Heil - Simona Rossi - Stefania Battistini - Fabio Giannini - Nila Volpi - Frederik J Steyn - Shyuan T Ngo - Elisabetta Ferraro - Luca Madaro - Roberto Coccurello - Cristiana Valle - Alberto Ferri - A DTI study of leukoaraiosis and the differential diagnosis between leukoaraiosis and acute lacunar infarction., CNS neuroscience & therapeutics | 2019
Auteur(s) : De-Qiang Zhao - Zhan-Wen Wang - Ying Cheng - Zhen Yuan - Frédérique René - Haoyi Liu - Artem Pliss - Ping Luan - Ambroxol Hydrochloride Improves Motor Functions and Extends Survival in a Mouse Model of Familial Amyotrophic Lateral Sclerosis., Frontiers in pharmacology | 2019
Auteur(s) : Alexandra Bouscary - Cyril Quessada - Althéa Mosbach - Noëlle Callizot - Michael Spedding - Jean-Philippe Loeffler - Alexandre Henriques - Morphological MRI investigations of the hypothalamus in 232 individuals with Parkinson's disease., Movement disorders : official journal of the Movement Disorder Society | 2019
Auteur(s) : Martin Gorges - Barbara Kuntz - Kelly Del Tredici - Daniel G Schmidt - Hans-Peter Müller - Albert C Ludolph - Luc Dupuis - Jan Kassubek - Association of Serum Retinol-Binding Protein 4 Concentration With Risk for and Prognosis of Amyotrophic Lateral Sclerosis., JAMA neurology | 2018
Auteur(s) : Angela Rosenbohm - Gabriele Nagel - Raphael S Peter - Torben Brehme - Wolfgang Koenig - Luc Dupuis - Dietrich Rothenbacher - Albert C Ludolph - ALS Registry Study Group - Could Conservative Iron Chelation Lead to Neuroprotection in Amyotrophic Lateral Sclerosis?, Antioxidants & redox signaling | 2018
Auteur(s) : Caroline Moreau - Véronique Danel - Jean Christophe Devedjian - Guillaume Grolez - Kelly Timmerman - Charlotte Laloux - Maud Petrault - Flore Gouel - Aurélie Jonneaux - Mary Dutheil - Cédrick Lachaud - Renaud Lopes - Grégory Kuchcinski - Florent Auger - Maeva Kyheng - Alain Duhamel - Thierry Pérez - Pierre François Pradat - Hélène Blasco - Charlotte Veyrat-Durebex - Philippe Corcia - Patrick Oeckl - Markus Otto - Luc Dupuis - Guillaume Garçon - Luc Defebvre - Z Ioav Cabantchik - James Duce - Régis Bordet - David Devos - J-1203 - Daunorubicin reduces MBNL1 sequestration caused by CUG-repeat expansion and rescues cardiac dysfunctions in a Drosophila model of myotonic dystrophy., Disease Models and Mechanisms | 2018
Auteur(s) : Mouli Chakraborty - Chantal Sellier - Michel Ney - Pascal Villa - Nicolas Charlet-Berguerand - Ruben Artero - Beatriz Llamusi - Hypertonic Stress Causes Cytoplasmic Translocation of Neuronal, but Not Astrocytic, FUS due to Impaired Transportin Function., Cell reports | 2018
Auteur(s) : Eva-Maria Hock - Zuzanna Maniecka - Marian Hruska-Plochan - Stefan Reber - Florent Laferrière - Sonu Sahadevan M K - Helena Ederle - Lauren Gittings - Lucas Pelkmans - Luc Dupuis - Tammaryn Lashley - Marc-David Ruepp - Dorothee Dormann - Magdalini Polymenidou - Hypothalamic Alterations in Neurodegenerative Diseases and Their Relation to Abnormal Energy Metabolism., Frontiers in molecular neuroscience | 2018
Auteur(s) : Pauline Vercruysse - Didier Vieau - David Blum - Åsa Petersén - Luc Dupuis - Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers., Acta Neuropathologica Communications | 2018
Auteur(s) : Petra Frick - Chantal Sellier - Ian R A Mackenzie - Chieh-Yu Cheng - Julie Tahraoui-Bories - Cecile Martinat - R Jeroen Pasterkamp - Johannes Prudlo - Dieter Edbauer - Mustapha Oulad-Abdelghani - Regina Feederle - Nicolas Charlet-Berguerand - Manuela Neumann - 74580 - 310659 - Paradox of amyotrophic lateral sclerosis and energy metabolism., Journal of neurology, neurosurgery, and psychiatry | 2018
Auteur(s) : Rebekah M Ahmed - Luc Dupuis - Matthew C Kiernan - Repeat-associated non-AUG (RAN) translation and other molecular mechanisms in Fragile X Tremor Ataxia Syndrome., Brain research | 2018
Auteur(s) : M Rebecca Glineburg - Peter K Todd - Nicolas Charlet-Berguerand - Chantal Sellier - R01 NS086810 - I01 BX003231 - T32 NS007222 - I21 BX001841 - R01 NS099280 - Reversible induction of TDP-43 granules in cortical neurons after traumatic injury., Experimental neurology | 2018
Auteur(s) : Diana Wiesner - Lilla Tar - Birgit Linkus - Akila Chandrasekar - Florian Olde Heuvel - Luc Dupuis - William Tsao - Philip C Wong - Albert Ludolph - Francesco Roselli - T32 GM007309 - Safety and efficacy of rasagiline as an add-on therapy to riluzole in patients with amyotrophic lateral sclerosis: a randomised, double-blind, parallel-group, placebo-controlled, phase 2 trial., The Lancet. Neurology | 2018
Auteur(s) : Albert C Ludolph - Joachim Schuster - Johannes Dorst - Luc Dupuis - Jens Dreyhaupt - Jochen H Weishaupt - Jan Kassubek - Ulrike Weiland - Susanne Petri - Thomas Meyer - Julian Grosskreutz - Berthold Schrank - Matthias Boentert - Alexander Emmer - Andreas Hermann - Daniel Zeller - Johannes Prudlo - Andrea S Winkler - Torsten Grehl - Michael T Heneka - Siw Wollebæk Johannesen - Bettina Göricke - RAS-ALS Study Group - The VAMP-associated protein VAPB is required for cardiac and neuronal pacemaker channel function., FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 2018
Auteur(s) : Nicole Silbernagel - Magdalena Walecki - Martin K-H Schäfer - Mirjam Kessler - Mehrnoush Zobeiri - Susanne Rinné - Aytug K Kiper - Marlene A Komadowski - Kirsty S Vowinkel - Konstantin Wemhöner - Lisa Fortmüller - Marcus Schewe - Amalia M Dolga - Jelena Scekic-Zahirovic - Lina A Matschke - Carsten Culmsee - Thomas Baukrowitz - Laurent Monassier - Nina D Ullrich - Luc Dupuis - Steffen Just - Thomas Budde - Larissa Fabritz - Niels Decher - FS/13/43/30324 - Thermoregulation in amyotrophic lateral sclerosis., Handbook of clinical neurology | 2018
Auteur(s) : Luc Dupuis - Åsa Petersen - Patrick Weydt - Thermoregulatory disorders in Huntington disease., Handbook of clinical neurology | 2018
Auteur(s) : Patrick Weydt - Luc Dupuis - Åsa Petersen - Unmasking the skiptic task of TDP-43, The EMBO journal | 2018
Auteur(s) : Caroline Rouaux - Jose-luis Gonzalez De Aguilar - Luc Dupuis - rbFOX1/MBNL1 competition for CCUG RNA repeats binding contributes to myotonic dystrophy type 1/type 2 differences., Nature communications | 2018
Auteur(s) : Chantal Sellier - Estefanía Cerro-Herreros - Markus Blatter - Fernande Freyemuth - Angeline Gaucherot - Frank Ruffenach - Partha Sarkar - Jack Puymirat - Bjarne Udd - John W Day - Giovanni Meola - Guillaume Bassez - Harutoshi Fujimura - Masanori P Takahashi - Benedikt Schoser - Denis Furling - Ruben Artero - Frédéric H T Allain - Beatriz Llamusi - Nicolas Charlet-Berguerand - 310659 - ALS-causing mutations differentially affect PGC-1α expression and function in the brain vs. peripheral tissues., Neurobiology of disease | 2017
Auteur(s) : Hanna Bayer - Kerstin Lang - Eva Buck - Julia Higelin - Lara Barteczko - Noemi Pasquarelli - Jasmin Sprissler - Tanja Lucas - Karlheinz Holzmann - Maria Demestre - Katrin S Lindenberg - Karin M Danzer - Tobias Boeckers - Albert C Ludolph - Luc Dupuis - Patrick Weydt - Anke Witting - Adipokines, C-reactive protein and Amyotrophic Lateral Sclerosis - results from a population- based ALS registry in Germany., Scientific reports | 2017
Auteur(s) : Gabriele Nagel - Raphael S Peter - Angela Rosenbohm - Wolfgang Koenig - Luc Dupuis - Dietrich Rothenbacher - Albert C Ludolph - Degeneration of serotonin neurons triggers spasticity in amyotrophic lateral sclerosis., Annals of neurology | 2017
Auteur(s) : Hajer El Oussini - Jelena Scekic - Pauline Vercruysse - Christine Marques - Sylvie Dirrig-Grosch - Stephane Dieterle - Gina Picchiarelli - Jerome Sinniger - Caroline Rouaux - Luc Dupuis - Dysregulation of chromatin remodelling complexes in amyotrophic lateral sclerosis., Human molecular genetics | 2017
Auteur(s) : Michael Tibshirani - Beibei Zhao - Benoit J Gentil - Sandra Minotti - Christine Marques - Julia Keith - Ekaterina Rogaeva - Lorne Zinman - Caroline Rouaux - Janice Robertson - Heather D Durham - Hypothalamic atrophy is related to body mass index and age at onset in amyotrophic lateral sclerosis., Journal of neurology, neurosurgery, and psychiatry | 2017
Auteur(s) : Martin Gorges - Pauline Vercruysse - Hans-Peter Müller - Hans-Jürgen Huppertz - Angela Rosenbohm - Gabriele Nagel - Patrick Weydt - Åsa Petersén - Albert C Ludolph - Jan Kassubek - Luc Dupuis - Inhibition of β-Glucocerebrosidase Activity Preserves Motor Unit Integrity in a Mouse Model of Amyotrophic Lateral Sclerosis., Scientific reports | 2017
Auteur(s) : Alexandre Henriques - Mylene Huebecker - Hélène Blasco - Céline Keime - Christian R Andres - Philippe Corcia - David A Priestman - Frances M Platt - Michael Spedding - Jean-Philippe Loeffler - Life course body mass index and risk and prognosis of amyotrophic lateral sclerosis: results from the ALS registry Swabia., European journal of epidemiology | 2017
Auteur(s) : Raphael Simon Peter - Angela Rosenbohm - Luc Dupuis - Torben Brehme - Jan Kassubek - Dietrich Rothenbacher - Gabriele Nagel - Albert Christian Ludolph - 577631 - 577631 - 577631 - Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis., Acta neuropathologica | 2017
Auteur(s) : Jelena Scekic-Zahirovic - Hajer El Oussini - Sina Mersmann - Kevin Drenner - Marina Wagner - Ying Sun - Kira Allmeroth - Stéphane Dieterlé - Jérôme Sinniger - Sylvie Dirrig-Grosch - Frédérique René - Dorothee Dormann - Christian Haass - Albert C Ludolph - Clotilde Lagier-Tourenne - Erik Storkebaum - Luc Dupuis - 321366 - Regulatory Role of RNA Chaperone TDP-43 for RNA Misfolding and Repeat-Associated Translation in SCA31., Neuron | 2017
Auteur(s) : Taro Ishiguro - Nozomu Sato - Morio Ueyama - Nobuhiro Fujikake - Chantal Sellier - Akemi Kanegami - Eiichi Tokuda - Bita Zamiri - Terence Gall-Duncan - Mila Mirceta - Yoshiaki Furukawa - Takanori Yokota - Keiji Wada - J Paul Taylor - Christopher E Pearson - Nicolas Charlet-Berguerand - Hidehiro Mizusawa - Yoshitaka Nagai - Kinya Ishikawa - - R35 NS097974 - Sphingolipid Metabolism Is Dysregulated at Transcriptomic and Metabolic Levels in the Spinal Cord of an Animal Model of Amyotrophic Lateral Sclerosis., Frontiers in Molecular Neuroscience | 2017
Auteur(s) : Alexandre Henriques - Vincent Croixmarie - Alexandra Bouscary - Althéa Mosbach - Céline Keime - Claire Boursier-Neyret - Bernard Walter - Michael Spedding - Jean-Philippe Loeffler - A transgenic mouse expressing CHMP2Bintron5 mutant in neurons develops histological and behavioural features of amyotrophic lateral sclerosis and frontotemporal dementia., Human molecular genetics | 2016
Auteur(s) : Aurelia Vernay - Ludivine Therreau - Béatrice Blot - Valérie Risson - Sylvie Dirrig-Grosch - Robin Waegaert - Thiebault Lequeu - Francois Sellal - Laurent Schaeffer - Rémy Sadoul - Jean-Philippe Loeffler - Frédérique René - APP-dependent glial cell line-derived neurotrophic factor gene expression drives neuromuscular junction formation., FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 2016
Auteur(s) : Serena Stanga - Nadège Zanou - Emilie Audouard - Bernadette Tasiaux - Sabrina Contino - Gaëlle Vandermeulen - Frédérique René - Jean-Philippe Loeffler - Frédéric Clotman - Philippe Gailly - Ilse Dewachter - Jean-Noël Octave - Pascal Kienlen-Campard - Alterations in the hypothalamic melanocortin pathway in amyotrophic lateral sclerosis., Brain : a journal of neurology | 2016
Auteur(s) : Pauline Vercruysse - Jérôme Sinniger - Hajer El Oussini - Jelena Scekic - Stephane Dieterle - Reinhard Dengler - Thomas Meyer - Stephan Zierz - Jan Kassubek - Wilhelm Fischer - Jens Dreyhaupt - Torsten Grehl - Andreas Hermann - Julian Grosskreutz - Anke Witting - Ludo Van Den Bosch - Odile Spreux-Varoquaux - Albert C Ludolph - Luc Dupuis - GERP ALS Study Group - Body fat distribution in Parkinson's disease: An MRI-based body fat quantification study., Parkinsonism & related disorders | 2016
Auteur(s) : Denise Bernhardt - Hans-Peter Müller - Albert C Ludolph - Luc Dupuis - Jan Kassubek - Evaluating Behavior in Mouse Models of the Behavioral Variant of Frontotemporal Dementia: Which Test for Which Symptom?, Neuro-degenerative diseases | 2016
Auteur(s) : Aurelia Vernay - Francois Sellal - Frédérique René - Serotonin 2B receptor slows disease progression and prevents degeneration of spinal cord mononuclear phagocytes in amyotrophic lateral sclerosis., Acta neuropathologica | 2016
Auteur(s) : Hajer El Oussini - Hanna Bayer - Jelena Scekic-Zahirovic - Pauline Vercruysse - Jérôme Sinniger - Sylvie Dirrig-Grosch - Stéphane Dieterlé - Yon Andoni Echaniz-laguna - Yves Larmet - Kathrin Müller - Jochen H Weishaupt - Dietmar R Thal - Wouter van Rheenen - Kristel van Eijk - Roland Lawson - Laurent Monassier - Luc Maroteaux - Anne Roumier - Philip C Wong - Leonard H van den Berg - Albert C Ludolph - Jan H Veldink - Anke Witting - Luc Dupuis - Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy., Nature communications | 2016
Auteur(s) : Fernande Freyermuth - Frédérique Rau - Yosuke Kokunai - Thomas Linke - Chantal Sellier - Masayuki Nakamori - Yoshihiro Kino - Ludovic Arandel - Arnaud Jollet - Christelle Thibault-Carpentier - Muriel Philipps - Serge Vicaire - Bernard Jost - Bjarne Udd - John W Day - Denis Duboc - Karim Wahbi - Tsuyoshi Matsumura - Harutoshi Fujimura - Hideki Mochizuki - François Deryckere - Takashi Kimura - Nobuyuki Nukina - Shoichi Ishiura - Vincent Lacroix - Amandine Campan-Fournier - Vincent Navratil - Emilie Chautard - Didier Auboeuf - Minoru Horie - Keiji Imoto - Kuang-Yung Lee - Maurice S Swanson - Adolfo Lopez de Munain - Shin Inada - Hideki Itoh - Kazuo Nakazawa - Takashi Ashihara - Eric Wang - Thomas Zimmer - Denis Furling - Masanori P Takahashi - Nicolas Charlet-Berguerand - 310659 - DP5 OD017865 - P01 NS058901 - The Role of Skeletal Muscle in Amyotrophic Lateral Sclerosis, Brain pathology | 2016
Auteur(s) : Jean-Philippe Loeffler - Gina Picchiarelli - Luc Dupuis - Jose-luis Gonzalez De Aguilar - The most prevalent genetic cause of ALS-FTD, C9orf72 synergizes the toxicity of ATXN2 intermediate polyglutamine repeats through the autophagy pathway., Autophagy | 2016
Auteur(s) : Sorana Ciura - Chantal Sellier - Maria-Letizia Campanari - Nicolas Charlet-Berguerand - Edor Kabashi - 310659 - Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss., The EMBO journal | 2016
Auteur(s) : Jelena Scekic-Zahirovic - Oliver Sendscheid - Hajer El Oussini - Mélanie Jambeau - Ying Sun - Sina Mersmann - Marina Wagner - Stéphane Dieterlé - Jérôme Sinniger - Sylvie Dirrig-Grosch - Kevin Drenner - Marie-Christine Birling - Jinsong Qiu - Yu Zhou - Hairi Li - Xiang-Dong Fu - Caroline Rouaux - Tatyana Shelkovnikova - Anke Witting - Albert C Ludolph - Friedemann Kiefer - Erik Storkebaum - Clotilde Lagier-Tourenne - Luc Dupuis - Blood Cell Palmitoleate-Palmitate Ratio Is an Independent Prognostic Factor for Amyotrophic Lateral Sclerosis, PloS one | 2015
Auteur(s) : Alexandre Henriques - Hélène Blasco - Marie-Céline Fleury - Philippe Corcia - Yon Andoni Echaniz-Laguna - Laura Robelin - Gabrielle Rudolf - Thiebault Lequeu - Martine Bergaentzle - Christian Gachet - Pierre-François Pradat - Eric Marchioni - Christian R Andres - Christine Tranchant - Jose-luis Gonzalez De Aguilar - Jean-Philippe Loeffler - Gene expression changes in spinal motoneurons of the SOD1(G93A) transgenic model for ALS after treatment with G-CSF, Frontiers in cellular neuroscience | 2015
Auteur(s) : Alexandre Henriques - Stefan Kastner - Eva Chatzikonstantinou - Claudia Pitzer - Christian Plaas - Friederike Kirsch - Oliver Wafzig - Carola Krüger - Robert Spoelgen - Jose-luis Gonzalez De Aguilar - Norbert Gretz - Armin Schneider