GPR139: A Novel Therapeutic Target to Alleviate Opioid Withdrawal Symptoms
The Preclinical Addictions Team is exploring a new therapeutic avenue involving the GPR139 receptor.
Embrace interdisciplinarity!
On 9 April 2026, the “Embracing Interdisciplinarity” event brought together researchers from the various ITIs at the University of Strasbourg.
Social Environment and Addictive Behaviors: What Is the Connection?
In an interview with Savoir(s), Victor Mathis, a research scientist in the Addictions team at Unit 1329, “Translational Neuroscience and Psychiatry” in Strasbourg, discusses the influence of the social environment on opioid and psychostimulant use through various preclinical studies.
Podcast: Research and Care United Against Opioid Addiction
Discover this podcast produced in collaboration with Inserm Est and RCF Alsace, which explores research into the mechanisms underlying addiction conducted by the “Addictions” team at Unit U1329, Translational Neuroscience and Psychiatry in Strasbourg, co-led by Laurence Lalanne and Emmanuel Darcq.
Research brings new hope for Amyotrophic Lateral Sclerosis
To mark Brain Awareness Week, Luc Dupuis, Director of UMR-S 1329, was a guest on the “Focus en Alsace” program on RFC Alsace radio.
What if the first signs of ALS were found... in sleep?
In a video interview with Inserm, Matei Bolborea discusses the findings of a recently published paper suggesting that detailed sleep analysis could serve as an early indicator of ALS progression.
Visual rehabilitation at the heart of a European research program
Want to know more about the European study run by Dr. Reber on visual rehabilitation? Check the video made by University of Strasbourg.
Incubation of social deficit during morphine abstinence in male mice using a novel unbiased and automatized method
Face of the global opioid addiction epidemic and the frequent relapses observed after withdrawal, understanding the brain and behavioral mechanisms of abstinence has become a major public health challenge. The work of Victor MATHIS and Emmanuel DARCQ addresses this issue by exploring how opioid…
The neural circuits and signalling pathways of opioid use disorder
This review from Nature Reviews Neuroscience, written by our two researchers, Emmanuel DARCQ and Victor MATHIS, in collaboration with Aliza EHRLICH, highlights recent advances in our understanding of opioid receptors and the neural circuits in which they operate (including the broad network of…
11th French ALS and MND Research Days
Isabelle Weber rewarded at the 11th French ALS and MND Research Days.
Two prizes for PhD students in the Psychiatry team
Several pieces of good news in October for former and current PhD students in the Psychiatry team.
ESF funding: visual rehabilitation and virtual reality
Michael Reber, an INSERM researcher in the Psychiatry team, has secured €1.2 million in funding from the European Science Foundation under the Fight Kids Cancer programme for a European study involving seven countries (France, Denmark, the Netherlands, Austria, Italy, the United Kingdom, and Spain).
Rethinking addiction
Rethinking addiction: Technological advances, mechanistic insights and the re-evaluation of substance use disorders. This collection of scientific articles explores how emerging technologies, ranging from neuroscience tools to behavioral modeling, are reshaping our understanding of addiction and…
Body Self symposium
On 20 and 21 March 2025, the international symposium ‘The Sense of Self: One Body, Multiple Mechanisms’ was held at the Dental Surgery Centre.
Brain Week
Held every year in March, Brain Week is an international event organized simultaneously in some 100 countries and over 120 towns in France, to raise public awareness of the importance of brain research.
Amyotrophic Lateral Sclerosis: sleep disorders precede the onset of motor symptoms
Sleep disorders are well known in several neurodegenerative diseases, but remain little studied in the case of amyotrophic lateral sclerosis (ALS). In this new study by Guillot, Lang et al., the authors focus on sleep changes and imbalances in hypothalamic signals in ALS patients. Using sleep…
NeuroStra Scientific Day 2024
Marina Hernán Godoy and LingYi Zhang, both PhD students in the ALS-FTD team, awarded at the NeuroStra Scientific Day 2024.