GPR139: A Novel Therapeutic Target to Alleviate Opioid Withdrawal Symptoms
The Preclinical Addictions Team is exploring a new therapeutic avenue involving the GPR139 receptor.
Social Environment and Addictive Behaviors: What Is the Connection?
In an interview with Savoir(s), Victor Mathis, a research scientist in the Addictions team at Unit 1329, “Translational Neuroscience and Psychiatry” in Strasbourg, discusses the influence of the social environment on opioid and psychostimulant use through various preclinical studies.
Podcast: Research and Care United Against Opioid Addiction
Discover this podcast produced in collaboration with Inserm Est and RCF Alsace, which explores research into the mechanisms underlying addiction conducted by the “Addictions” team at Unit U1329, Translational Neuroscience and Psychiatry in Strasbourg, co-led by Laurence Lalanne and Emmanuel Darcq.
Incubation of social deficit during morphine abstinence in male mice using a novel unbiased and automatized method
Face of the global opioid addiction epidemic and the frequent relapses observed after withdrawal, understanding the brain and behavioral mechanisms of abstinence has become a major public health challenge. The work of Victor MATHIS and Emmanuel DARCQ addresses this issue by exploring how opioid…
The neural circuits and signalling pathways of opioid use disorder
This review from Nature Reviews Neuroscience, written by our two researchers, Emmanuel DARCQ and Victor MATHIS, in collaboration with Aliza EHRLICH, highlights recent advances in our understanding of opioid receptors and the neural circuits in which they operate (including the broad network of…
Rethinking addiction
Rethinking addiction: Technological advances, mechanistic insights and the re-evaluation of substance use disorders. This collection of scientific articles explores how emerging technologies, ranging from neuroscience tools to behavioral modeling, are reshaping our understanding of addiction and…
Brain Week
Held every year in March, Brain Week is an international event organized simultaneously in some 100 countries and over 120 towns in France, to raise public awareness of the importance of brain research.
Doctoral grants and 4th-year thesis funding
Dersu OZDEMIR, a PhD student in her 4th year, and Solène POIVEY, a future PhD student, have both obtained funding to continue their work in the Addictions team.
A new step in characterizing the emotional consequences of opioid withdrawal
The University of Strasbourg's Savoir(s) newspaper spotlights the Addictions team!