Presentation

The STEP laboratory conducts multidisciplinary neurobiology research into neurodegenerative and psychiatric pathologies, focusing in particular on diagnostic and therapeutic aspects.

It is organized around 3 teams:

•     Psychiatry team headed by Dr Anne Giersch. Their research aims to understand the pathophysiology of psychiatric illnesses: schizophrenia, addiction and depression, ADHD and bipolar disorders. Aims: find markers for these illnesses and seek new therapeutic targets.
•     Addictions team, co-directed by Dr Laurence Lalanne and Dr Emmanuel Darcq. It studies the mechanisms of addictive disorders to opioids, alcohol and cannabis, in relation to psychiatric comorbidities.
•     SLA-DFT team led by Dr Caroline Rouaux. The team's research focuses on amyotrophic lateral sclerosis (ALS) and fronto-temporal dementia (FTD), two related neurodegenerative diseases considered as the two extremes of a genetic, pathological and clinical continuum.